Just steps from the fabled, dramatic Charles Bridge, this intimate, historic retreat promises a very personal touch with storybook charm and gracious, intuitive service. The Alchymist Grand Hotel and Spa represents the renaissance of a magnificent Baroque landmark, ""D?m u Je?í?ka"" dating from the 16th century and exquisitely transformed with the most modern comforts into a luxury and distinctive hotel that reflects the nobility and charm of historic Prague. If looking for a luxury boutique hotel in the very centre of Prague, the Alchymist Grand Hotel and Spa is the place to be. This beautiful pearl and masterpiece is the prominent Prague luxury hotel of choice for many celebrities and discerning travelers.